GnusBiff is „too primitive“ according to its own description
Desktop Notifications
GnusNotifications is included with GNUs itself, uses the ‘notifications’ library that comes with emacs 24. It allows to set a minimum group level to hide notifications and fetch profile photos using the sender address and google+.
GnusDesktopNotify can be configured per-group, can collapse group names, and also call any arbitrary function/program in response to new mail.